The accident, which occurred in the early hours of Wednesday, involved a Kia Granbird bus with registration number GT 6068-19 and a Kia Rhino truck with registration number GR 7968-20.
The suspect driver, Yakubu, in charge of the KIA Granbird bus, was transporting 28 passengers from Kumasi to Tamale.
Upon reaching a section of the road at Mile 40, the bus collided head-on with the KIA Rhino, which was carrying watermelons from Daboya to Goaso.
Occupants of both vehicles sustained various degrees of injuries and were rushed to the Central Gonja District Hospital in Buipe for treatment.
Unfortunately, three male adults, including both drivers, two females, and a child, died on the spot.
The Ghana National Fire Service (GNFS) in Buipe was called to the scene to assist in extricating victims and clearing the accident site.
Their bodies have been deposited at the Central Gonja District Hospital morgue for preservation, pending autopsy.
Meanwhile, the Buipe District Police Command, led by its Crime Officer, ASP Amoako, has appealed to drivers to reduce their speed to save lives.